Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | ESR1 | P03372 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | ELANE | P08246 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.61 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312147 | 0.85 | KMT2A (0.76) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL11767220 | 0.85 | ESR1 (0.66) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL11445596 | 0.83 | KMT2A (0.73) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| Diethylstilbestrol Dipropionate SCHEMBL151730 | 0.82 | KMT2A (1.00) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL5690655 | 0.82 | KMT2A (0.72) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| Diethylstilbestrol Dipropionate SCHEMBL2440005 | 0.82 | KMT2A (1.00) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL28216941 | 0.82 | PARP10 (0.57) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL11374349 | 0.82 | KMT2A (0.72) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL11662255 | 0.81 | KMT2A (0.66) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL968516 | 0.81 | KMT2A (0.70) | KMT2AESR1HIF1ASMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |