SCHEMBL23035129

SCHEMBL23035129

O=S(=O)(NCl)c1ccc(C(F)(F)F)cn1.[NaH]

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 11/20 0.46
KIT P10721 1/20 0.45
POLB P06746 2/20 0.44
KIF11 P52732 1/20 0.41
KMT2A Q03164 2/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
MEN1 O00255 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22446699 0.98 PPARD (0.47) PPARDKITPOLBKIF11KMT2A
SCHEMBL1300785 0.79 POLB (0.48) PPARDPOLBKIF11KMT2ACNR1
Ammonia Solution, Strong SCHEMBL27471941 0.77 POLB (0.47) PPARDPOLBKIF11KMT2ACNR1
SCHEMBL8430620 0.77 POLB (0.50) PPARDPOLBKIF11KMT2ACNR1
SCHEMBL28654691 0.77 POLB (0.49) PPARDPOLBKIF11KMT2ACNR1
SCHEMBL5597568 0.76 KIT (0.53) PPARDKITKIF11KMT2AMEN1
SCHEMBL3126218 0.75 POLB (0.52) PPARDKITPOLBKIF11KMT2A
SCHEMBL12412755 0.75 POLB (0.48) PPARDPOLBKIF11KMT2ACNR1
SCHEMBL3702320 0.75 POLB (0.51) PPARDPOLBKIF11KMT2ACNR1
SCHEMBL2702353 0.75 CA1 (0.55) PPARDKITPOLBKIF11KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3548475-B1 SULFONAMIDE ANALOGUES OF GALIELLALACTONE GLACTONE PHARMA DEV AB (SE) 2021-03-03 EP disclosed