Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761716 | 0.83 | MAPT (0.53) | KITTSHRL3MBTL1KMT2ALMNA | |
| SCHEMBL8366958 | 0.81 | KIT (0.50) | KITKMT2AMEN1LMNAMAPT | |
| SCHEMBL14416437 | 0.80 | PPARG (0.47) | KITKMT2AMEN1MAPTHTT | |
| SCHEMBL22446699 | 0.78 | PPARD (0.47) | KITKMT2AMEN1KIF11PPARD | |
| SCHEMBL23035129 | 0.76 | PPARD (0.46) | KITKMT2AMEN1KIF11PPARD | |
| SCHEMBL7572845 | 0.76 | KMT2A (0.67) | KMT2AMEN1ARNR1H3ALDH1A1 | |
| SCHEMBL14416436 | 0.75 | MLNR (0.46) | KITKMT2AMEN1LMNAMAPT | |
| SCHEMBL14416440 | 0.75 | MLNR (0.52) | KITKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL27214218 | 0.73 | SLC40A1 (0.72) | AGTR1 | |
| SCHEMBL28654691 | 0.73 | POLB (0.49) | KMT2AKIF11PPARDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814549-A2 | METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND UK-427, 857 | Boehringer Ingelheim International GmbH (DE) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055660-A2 | METHOD FOR TREATING HIV INFECTION THROUGH CO-ADMINISTRATION OF TIPRANAVIR AND UK-427, 857 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-26 | — | — | WO | disclosed |