Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784914 | 0.90 | AKT1 (0.48) | SIGMAR1CTSKCTSSSYKAKT1 | |
| SCHEMBL17784913 | 0.90 | AKT1 (0.48) | SIGMAR1CTSKCTSSSYKAKT1 | |
| SCHEMBL23035087 | 0.81 | AKT1 (0.50) | SIGMAR1CTSKCTSSSYKAKT1 | |
| SCHEMBL23035088 | 0.81 | AKT1 (0.50) | SIGMAR1CTSKCTSSSYKAKT1 | |
| SCHEMBL20578347 | 0.81 | CTSS (0.45) | CTSKCTSSAKT1 | |
| SCHEMBL20578346 | 0.81 | CTSS (0.45) | CTSKCTSSAKT1 | |
| SCHEMBL20578302 | 0.80 | HPGD (0.38) | CTSKCTSSAKT1 | |
| SCHEMBL20578301 | 0.80 | HPGD (0.38) | CTSKCTSSAKT1 | |
| SCHEMBL20578332 | 0.80 | GAA (0.43) | AKT1 | |
| SCHEMBL20578055 | 0.80 | CACNA1B (0.42) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412665-B1 | SUVOREXANT INTERMEDIATES AND PREPARATION METHODS THEREOF | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2021-03-03 | — | — | EP | disclosed |