Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21073753 | 1.00 | APLNR (0.79) | APLNR | |
| SCHEMBL19735714 | 1.00 | APLNR (0.79) | APLNR | |
| SCHEMBL21073291 | 0.90 | APLNR (0.80) | APLNR | |
| SCHEMBL21073570 | 0.90 | APLNR (0.80) | APLNR | |
| SCHEMBL23035353 | 0.90 | APLNR (0.80) | APLNR | |
| SCHEMBL21073735 | 0.85 | APLNR (0.76) | APLNR | |
| SCHEMBL19717989 | 0.85 | APLNR (0.76) | APLNR | |
| SCHEMBL19717991 | 0.85 | APLNR (0.76) | APLNR | |
| SCHEMBL21135652 | 0.78 | APLNR (0.54) | APLNR | |
| SCHEMBL21073703 | 0.76 | APLNR (0.80) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | claimed |
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |