Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491218 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTPDGFRBPDGFRAKDM4E | |
| SCHEMBL21491372 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31472402 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23036750 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL21491412 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23036720 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL31472335 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23036732 | 0.72 | CHRNB4 (0.39) | ALDH1A1MAPTKDM4ECHRNB2CHRNB4 | |
| SCHEMBL21491186 | 0.71 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL23036825 | 0.71 | TSHR (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-A1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | Merck Patent GmbH (DE) | 2021-03-03 | — | — | EP | disclosed |