Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 1/20 | 1.00 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.97 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.97 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimetazidine SCHEMBL11846840 | 1.00 | CHRM2 (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL29375563 | 1.00 | CHRM2 (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL3896420 | 0.98 | CHRM2 (0.97) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL29605009 | 0.98 | APOBEC3A (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL580378 | 0.98 | APOBEC3A (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL15302482 | 0.98 | CHRM2 (0.97) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL2901538 | 0.98 | APOBEC3A (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL348591 | 0.98 | APOBEC3A (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL29677959 | 0.98 | APOBEC3A (1.00) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| Trimetazidine SCHEMBL12485382 | 0.97 | CHRM2 (0.94) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4212 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075493-A | Compound pharmaceutical preparation for treating chronic uricosuric nephropathy and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12616691-B2 | Use of fatty acid oxidation inhibitors as antimicrobials | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2026-05-05 | — | — | US | claimed |
| US-20260115145-A1 | Method for Enhancing Drug Solubility and Preparing a Drug Composite Material with Enhanced Solubility | PHARMAEASE TECH LTD (CN) | 2026-04-30 | — | — | US | claimed |
| EP-4731194-A1 | MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT | CSP Technologies, Inc. (US) | 2026-04-29 | — | — | EP | claimed |
| US-12599614-B2 | Methods and pharmaceutical compositions for the treatment and prophylaxis of microbial infectious diseases and associated inflammatory disorders and for the treatment and prophylaxis of aging and associated diseases | MD VAULT LLC (US) | 2026-04-14 | — | — | US | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4687805-A1 | MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF | CSP Technologies, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| US-20260027008-A1 | MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF | CSP TECHNOLOGIES, INC. | 2026-01-29 | — | — | US | claimed |
| EP-4023225-B1 | COMBINATIONS OF A SALICYLATE AND TRIMETAZIDINE FOR USE IN THE TREATMENT OF METABOLIC DISEASES | INST ZOOLOGY CAS (CN) | 2026-01-28 | — | — | EP | claimed |
| WO-2025264260-A1 | MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT | CSP TECHNOLOGIES, INC. (US) | 2025-12-26 | — | — | WO | claimed |
| EP-0673649-A1 | Pharmaceutical compositions for the prolonged release of trimetazidine after oral administration | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0453365-B1 | Process for the preparation of 1-(2,3,4-trimethoxybenzyl) piperazine by reductive amination | ADIR (FR) | 1994-11-30 | — | — | EP | claimed |
| EP-0613686-A1 | Use of trimetazidine for the preparation of medicaments for the treatment of troubles due to the therapeutical use of immunosuppressants | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | claimed |
| EP-0585155-A1 | Trifluoromethylketone derivatives of peptides having HLE inhibiting activity, their preparation and pharmaceutical composition | ADIR ET COMPAGNIE (FR) | 1994-03-02 | — | — | EP | claimed |
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | claimed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | claimed |
| US-5142053-A | PROCESS FOR THE PREPARATION OF 1-(2,3,4-TRIMETHOXYBENZYL)PIPERAZINE BY REDUCTIVE ANIMATION | ADIR ET COMPAGNIE (FR) | 1992-08-25 | — | — | US | claimed |
| EP-0453365-A1 | Process for the preparation of 1-(2,3,4-trimethoxybenzyl) piperazine by reductive amination | ADIR ET COMPAGNIE (FR) | 1991-10-23 | — | — | EP | claimed |
| US-4407801-A | HIGH DOSAGE OF 1-(2,3,4-TRIMETHOXYBENZYL)PIPERAZINE AND A DISINTEGRATING AGENT | SCIENCE UNION ET CIE (FR) | 1983-10-04 | — | — | US | claimed |
| US-3959281-A | CORONARY DILATORS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | claimed |