⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16289013 | 0.97 | POLB (0.31) | — | |
| SCHEMBL16568494 | 0.90 | — | — | |
| SCHEMBL30744244 | 0.89 | POLB (0.31) | — | |
| SCHEMBL27222209 | 0.89 | — | — | |
| SCHEMBL16288541 | 0.89 | — | — | |
| SCHEMBL16289630 | 0.88 | KDM4E (0.34) | — | |
| SCHEMBL16574822 | 0.86 | POLB (0.34) | — | |
| SCHEMBL16289348 | 0.85 | — | — | |
| SCHEMBL31683982 | 0.85 | POLB (0.33) | — | |
| SCHEMBL17964368 | 0.85 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |