Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.33 |
| ▸ | TK1 | P04183 | 4/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964368 | 0.92 | POLB (0.33) | POLBTYMSTK1 | |
| SCHEMBL31683982 | 0.92 | POLB (0.33) | POLBTYMSTK1 | |
| SCHEMBL16574847 | 0.92 | POLB (0.35) | POLBRNASE1 | |
| SCHEMBL16289011 | 0.91 | POLB (0.31) | POLB | |
| SCHEMBL29540185 | 0.90 | TERT (0.33) | POLBRNASE1 | |
| SCHEMBL16574834 | 0.90 | TERT (0.33) | POLBRNASE1 | |
| SCHEMBL16289013 | 0.90 | POLB (0.31) | POLB | |
| SCHEMBL16574864 | 0.90 | KDM4E (0.40) | POLB | |
| SCHEMBL22984007 | 0.89 | RNASE1 (0.40) | TYMSTK1RNASE1 | |
| SCHEMBL2031822 | 0.89 | RNASE1 (0.40) | TYMSTK1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891457-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | POLB 4572/4885TYMS 1920/4885TK1 3864/4885 |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | POLB 4572/4885TYMS 1920/4885TK1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.