SCHEMBL230397

SCHEMBL230397

CCCCCCc1cnnnn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
CYP19A1 P11511 6/20 0.37
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MIF P14174 1/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
PTGS2 P35354 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057663 1.00 KCNH2 (0.47) KCNH2CYP19A1HRH4HRH3ALDH1A1
Bromide SCHEMBL5723264 0.98 KCNH2 (0.46) KCNH2CYP19A1HRH4HRH3ALDH1A1
SCHEMBL10830973 0.98 KCNH2 (0.44) KCNH2CYP19A1HRH4HRH3ALDH1A1
Ammonia Solution, Strong SCHEMBL17372911 0.96 KCNH2 (0.42) KCNH2CYP19A1HRH4HRH3ALDH1A1
SCHEMBL11116422 0.92 KCNH2 (0.36) KCNH2HRH3ALDH1A1TDP1L3MBTL1
SCHEMBL2708608 0.74 KCNH2 (0.50) KCNH2CYP19A1ALDH1A1TDP1L3MBTL1
SCHEMBL29737342 0.74 KCNH2 (0.50) KCNH2CYP19A1ALDH1A1TDP1L3MBTL1
SCHEMBL29886625 0.74 KCNH2 (0.50) KCNH2CYP19A1ALDH1A1TDP1L3MBTL1
SCHEMBL28254740 0.74 KCNH2 (0.50) KCNH2CYP19A1ALDH1A1TDP1L3MBTL1
SCHEMBL28091636 0.74 KCNH2 (0.50) KCNH2CYP19A1ALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199947-A9 LIGHT-EMITTING COMPOSITION COMPRISING AN ORGANOSILOXANE SOLVENT AND PEROVSKITE NANOPARTICLES, AND A METHOD FOR PRODUCING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-06-20 US claimed
US-11724942-B2 Method for preparing a self-assembled porous three-dimensional zinc oxide nanoparticle structure using a microfluidic device, zinc oxide nanoparticles, an aggregate of zinc oxide nanoparticles, and zinc oxide nanoparticle structure prepared therefrom, and a bio-ink including the same JIN SU EON (KR) 2023-08-15 US claimed
US-20220389309-A1 LIGHT-EMITTING COMPOSITION COMPRISING AN ORGANOSILOXANE SOLVENT AND PEROVSKITE NANOPARTICLES, AND A METHOD FOR PRODUCING THE SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2022-12-08 US claimed
US-20220340441-A1 METHOD FOR PREPARING A SELF-ASSEMBLED POROUS THREE-DIMENSIONAL ZINC OXIDE NANOPARTICLE STRUCTURE USING A MICROFLUIDIC DEVICE, ZINC OXIDE NANOPARTICLES, AN AGGREGATE OF ZINC OXIDE NANOPARTICLES, AND ZINC OXIDE NANOPARTICLE STRUCTURE PREPARED THEREFROM, AND A BIO-INK INCLUDING THE SAME JIN SU EON (KR) 2022-10-27 US claimed
EP-3468923-B1 FLUORESCENT WATER TREATMENT COMPOUNDS AND METHOD OF USE ECOLAB USA INC (US) 2022-10-19 EP claimed
US-20220154132-A1 METHOD OF REDUCING CONCENTRATIONS OF ONE OR MORE OF N2O and NO IN MEDIUM SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-05-19 US claimed
WO-2022085886-A1 TITANIUM DIOXIDE COMPOSITE AND MANUFACTURING METHOD THEREFOR 성균관대학교산학협력단 2022-04-28 WO claimed
WO-2021033821-A1 METHOD FOR PRODUCING SELF-ASSEMBLED POROUS THREE-DIMENSIONAL ZINC OXIDE NANOPARTICLE STRUCTURE USING MICROFLUIDIC DEVICE, POROUS ZINC OXIDE NANOPARTICLES PRODUCED THEREBY, AGGREGATE OF SELF-ASSEMBLED POROUS ZINC OXIDE NANOPARTICLES, SELF-ASSEMBLED POROUS THREE-DIMENSIONAL ZINC OXIDE NANOPARTICLE STRUCTURE, AND BIO-INK INCLUDING SAME 진수언 2021-02-25 WO claimed
US-10654825-B2 Processes for making triazolo[4,5D] pyramidine derivatives and intermediates thereof CORVUS PHARMACEUTICALS, INC. (US) 2020-05-19 US claimed
EP-3600292-A1 PROCESSES FOR MAKING TRIAZOLO[4,5D]PYRAMIDINE DERIVATIVES AND INTERMEDIATES THEREOF Corvus Pharmaceuticals, Inc. (US) 2020-02-05 EP claimed
US-4376868-A Alkoxylation of cresylic acids CONOCO INC. (US) 1983-03-15 US claimed
US-4370256-A SULFATE OR SULFONATE ANIONIC SURFACTANT; MORPHOLINE, BENZOTRIAZOLE, HEXAMETHYLENETETRAMINE, PYRROLE, OR PYRAZINE THE DOW CHEMICAL COMPANY (US) 1983-01-25 US claimed
EP-0049358-A1 Strontium and barium containing alkoxylation systems for unsaturated alcohols Conoco Phillips Company (US) 1982-04-14 EP claimed
EP-0046947-A1 Strontium and barium containing alkoxylation systems Conoco Phillips Company (US) 1982-03-10 EP claimed
US-4311512-A Bactericidal water-soluble complexes POLYCRAFT LABORATORIES, INC., A CORP. OF NJ. 1982-01-19 US claimed
US-4253886-A Corrosion resistant ferromagnetic metal powders and method of preparing the same FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US claimed
US-4248638-A Method for preparing a magnesia carbon brick KUROSAKI YOGOYO CO., LTD., A CORP. OF JAPAN (JP) 1981-02-03 US claimed
US-4202882-A TETRAAZO FUSED HETEROCYCLE AND QUATERNARY AMMONIUM COMPOUND POLYCRAFT LABORATORIES, INC., A CORP. OF NJ. 1980-05-13 US claimed
US-4017462-A SOLUBILIZING WITH HYDROXYMETHYLPHOSPHONIUM SALTS AND FORMALDEHYDE, REACTION WITH PHENOLS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-04-12 US claimed
US-4012558-A Process for the manufacture of flame-resistant boards, a flame-retardant mixture and a flame-retardant bonding composition containing the same DEAD SEA BROMINE COMPANY LTD. (IL) 1977-03-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10654825-B2 Processes for making triazolo[4,5D] pyramidine derivatives and intermediates thereof IL5, THPO, PPOX KCNH2 1162/4885CYP19A1 536/4885HRH4 2545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.