SCHEMBL2303980

SCHEMBL2303980

CC(Cl)(Cl)Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
FDPS P14324 1/20 0.50
PNMT P11086 2/20 0.47
TAAR1 Q96RJ0 1/20 0.47
SIGMAR1 Q99720 6/20 0.43
TSHR P16473 2/20 0.42
CYP1A2 P05177 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
PYCR1 P32322 1/20 0.41
CYP2D6 P10635 1/20 0.41
TMEM97 Q5BJF2 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74006 0.84 IDO1 (0.52) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL15231686 0.82 IDO1 (0.54) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL11251872 0.81 FDPS (0.58) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL12215710 0.81 SLC6A2 (0.61) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL13144959 0.79 FDPS (0.47) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL27738563 0.76 IDO1 (0.52) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL17261450 0.75 FDPS (0.51) IDO1FDPSPNMTTAAR1TSHR
SCHEMBL9130780 0.75 FDPS (0.47) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL141241 0.75 FDPS (0.47) IDO1FDPSPNMTTAAR1SIGMAR1
SCHEMBL9422769 0.75 FDPS (0.47) IDO1FDPSPNMTTAAR1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8747666-B2 Methods and apparatuses for filtering water from a river or stream Melcher, Jeffrey S. (US) 2014-06-10 US disclosed
US-20130026107-A1 METHODS AND APPARATUSES FOR FILTERING WATER FROM OIL AND GAS WELLS Melcher, Jeffrey S. (US) 2013-01-31 US disclosed
US-7998344-B2 Methods and apparatuses for filtering water from oil and gas wells MILLER ROBERT L 2011-08-16 US disclosed
US-20090114609-A1 METHODS AND APPARATUSES FOR FILTERING WATER FROM OIL AND GAS WELLS MILLER ROBERT L 2009-05-07 US disclosed
US-20080035547-A1 METHODS AND APPARATUS FOR FILTERING WATER MELCHER, JEFFREY S. 2008-02-14 US disclosed
US-7179372-B2 Methods and apparatuses for filtering water Melcher, Jeffrey S. (US) 2007-02-20 US disclosed
US-20060180530-A1 Methods and apparatuses for filtering water MILLER ROBERT L 2006-08-17 US disclosed
US-7074337-B2 Methods and apparatuses for filtering water Melcher, Jeffrey S. (US) 2006-07-11 US disclosed
US-20050230325-A1 Methods and apparatuses for filtering water MELCHER, MR. JEFFREY S. 2005-10-20 US disclosed