Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074119 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL25775769 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL9385105 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL16013721 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL21207449 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL21207416 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL5080021 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL5074110 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL3476036 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 | |
| SCHEMBL26113224 | 1.00 | TLR4 (0.52) | TLR4LMNAZDHHC7GPR84TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733647-B1 | CATIONIC LIPID | EISAI R&D MAN CO LTD (JP) | 2022-06-15 | — | — | EP | disclosed |
| US-10947193-B2 | Cationic lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-3733647-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-20200308111-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-01 | — | — | US | disclosed |
| CN-111417621-A | Cationic lipids | 卫材R&D管理有限公司 | 2020-07-14 | — | — | CN | disclosed |
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | GLYTECH, INC. (JP) | 2014-09-04 | — | — | US | disclosed |
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | GLYTECH, INC. (JP) | 2014-09-04 | — | — | US | disclosed |
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | GLYTECH, INC. (JP) | 2014-09-04 | — | — | US | disclosed |
| US-8741871-B2 | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | GLYTECH, INC. (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8741871-B2 | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | GLYTECH, INC. (JP) | 2014-06-03 | — | — | US | disclosed |
| EP-2567963-A1 | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | Otsuka Chemical Co., Ltd. (JP) | 2013-03-13 | — | — | EP | disclosed |
| CN-102203110-A | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | OTSUKA CHEMICAL CO LTD | 2011-09-28 | — | — | CN | disclosed |
| US-20110218171-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110218171-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-09-08 | — | — | US | disclosed |
| EP-2351764-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | Otsuka Chemical Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308111-A1 | Cationic Lipid | NPC1L1, NPC1, LPCAT1 | TLR4 1098/4885LMNA 321/4885ZDHHC7 281/4885 |
| US-20110218171-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | TREH, MAN2B1, NFATC1 | TLR4 185/4885LMNA 1927/4885ZDHHC7 1407/4885 |
| US-20140248317-A1 | TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND | TREH, MAN2B1, NFATC1 | TLR4 185/4885LMNA 1927/4885ZDHHC7 1407/4885 |
| US-10947193-B2 | Cationic lipid | NPC1L1, NPC1, LPCAT1 | TLR4 1098/4885LMNA 321/4885ZDHHC7 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.