Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132555 | 1.00 | FDPS (0.48) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL14917005 | 0.77 | FDPS (0.45) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL6849061 | 0.76 | FDPS (0.43) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL3502980 | 0.76 | FDPS (0.44) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL3507321 | 0.76 | FDPS (0.44) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL10655090 | 0.76 | FDPS (0.44) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL321873 | 0.76 | FDPS (0.44) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL3502976 | 0.76 | FDPS (0.44) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL7718609 | 0.75 | GGPS1 (0.43) | FDPSGGPS1SMPD1CES2LPAR1 | |
| SCHEMBL3372046 | 0.75 | GGPS1 (0.43) | FDPSGGPS1SMPD1CES2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210062163-A1 | Stearoyl-ACP Desaturase and Variants Thereof Capable of Dioxygenase Chemistry and Converting Oleoyl-ACP to erythro-9,10-Dihydroxystearate | UNITED STATES DEPARTMENT OF ENERGY | 2021-03-04 | — | — | US | disclosed |