SCHEMBL23041007

SCHEMBL23041007

O=c1oc2cc(O)ccc2cc1P(=O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.58
MIF P14174 12/20 0.58
CA9 Q16790 2/20 0.58
ESR2 Q92731 1/20 0.55
KDM4E B2RXH2 4/20 0.54
MEN1 O00255 4/20 0.54
GLA P06280 4/20 0.54
GAA P10253 4/20 0.54
KMT2A Q03164 4/20 0.54
S1PR4 O95977 2/20 0.54
MAPT P10636 2/20 0.54
S1PR1 P21453 2/20 0.54
PTGS1 P23219 1/20 0.54
ALDH1A1 P00352 4/20 0.53
HPGD P15428 4/20 0.53
NPSR1 Q6W5P4 2/20 0.53
NPC1 O15118 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
TDP1 Q9NUW8 3/20 0.51
ERAP1 Q9NZ08 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30876784 0.79 HPGD (0.58) CA9ESR2KDM4EMEN1GAA
SCHEMBL4917067 0.79 HPGD (0.58) CA9ESR2KDM4EMEN1GAA
Phosphoric Acid SCHEMBL6259521 0.79 HSD17B3 (0.87) HSD17B3MIFCA9ESR2KDM4E
SCHEMBL23051357 0.78 MIF (0.55) HSD17B3MIFCA9ESR2KDM4E
SCHEMBL5296804 0.77 HSD17B3 (0.68) HSD17B3MIFCA9ESR2KDM4E
Phosphoric Acid SCHEMBL3273967 0.75 HSD17B3 (0.53) HSD17B3MIFCA9ESR2KDM4E
Phosphoric Acid SCHEMBL18762332 0.74 MIF (0.89) MIFESR2KDM4EMEN1GLA
Umbelliferone SCHEMBL2246676 0.74 CA9 (0.85) HSD17B3CA9ESR2KDM4EMEN1
SCHEMBL10789981 0.74 HSD17B3 (0.64) HSD17B3MIFCA9ESR2KDM4E
SCHEMBL1607902 0.74 HSD17B3 (0.64) HSD17B3MIFCA9ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021038306-A1 SELENOPHENOCHROMENE PHOSPHONIC ACIDS, PREPARATION AND USE AS ANTIPROLIFERATIVE AGENTS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2021-03-04 WO disclosed