Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Umbelliferone SCHEMBL18687146 | 0.84 | HPGD (0.69) | HSD17B3ESR2HPGDAKR1B1TYR | |
| SCHEMBL5306505 | 0.84 | CA12 (0.65) | HSD17B3ESR2HPGDAKR1B1TYR | |
| SCHEMBL10794401 | 0.81 | HSD17B3 (0.64) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL10789981 | 0.81 | HSD17B3 (0.64) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL10791318 | 0.81 | MIF (0.65) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL4077523 | 0.81 | AKR1B1 (0.59) | HSD17B3HPGDAKR1B1TYRDAO | |
| SCHEMBL1607902 | 0.81 | HSD17B3 (0.64) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL126040 | 0.81 | HSD17B3 (1.00) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL31015 | 0.79 | HSD17B3 (0.96) | HSD17B3ESR2HPGDAKR1B1MIF | |
| SCHEMBL1366686 | 0.79 | MIF (0.77) | HSD17B3HPGDAKR1B1MIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55111410-A | — | — | None | — | — | JP | disclosed |
| WO-2007012379-A2 | USE OF 3-HYDROXYCOUMARIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007012379-A2 | USE OF 3-HYDROXYCOUMARIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-02-01 | — | — | WO | disclosed |
| JP-S55111410-A | COSMETIC FOR MAKING FAIR SKIN | SANSHO SEIYAKU KK | 1980-08-28 | — | — | JP | disclosed |