Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624762 | 0.77 | — | — | |
| SCHEMBL16752030 | 0.73 | CHRM1 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11357865 | 0.73 | CHRM1 (0.39) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL30421474 | 0.73 | TSHR (0.33) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL30446842 | 0.72 | FFAR3 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL1357297 | 0.72 | FFAR3 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL8777797 | 0.72 | FFAR3 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL8777834 | 0.72 | FFAR3 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL31122181 | 0.72 | FFAR3 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2768344 | 0.71 | TDP1 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349992-B1 | THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2349992-A1 | THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM | Momentive Performance Materials Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010051396-A1 | THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| US-7674861-B1 | Thiocarbamoyldisufanyl-functional cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-03-09 | — | — | US | disclosed |