SCHEMBL230424

SCHEMBL230424

Clc1ccccc1N1CCNCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 4/20 1.00
DRD2 P14416 2/20 0.75
DRD3 P35462 2/20 0.75
HTR1A P08908 5/20 0.61
HTR3A P46098 4/20 0.61
CYP1A2 P05177 3/20 0.61
CYP2D6 P10635 3/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2C9 P11712 2/20 0.61
HTR7 P34969 4/20 0.58
HTR6 P50406 3/20 0.58
HTR2A P28223 2/20 0.58
HTR5A P47898 2/20 0.58
HTR3E A5X5Y0 2/20 0.58
HTR3B O95264 2/20 0.58
HTR3D Q70Z44 2/20 0.58
HTR3C Q8WXA8 2/20 0.58
SIGMAR1 Q99720 2/20 0.58
NCF1 P14598 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5785574 1.00 ADRB1 (1.00) ADRB1DRD2DRD3HTR1AHTR3A
SCHEMBL29446047 1.00 ADRB1 (1.00) ADRB1DRD2DRD3HTR1AHTR3A
Water SCHEMBL27802433 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Hydrochloric Acid SCHEMBL184663 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Hydrochloric Acid SCHEMBL6577765 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Piperazine SCHEMBL28142154 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Hydrochloric Acid SCHEMBL29777392 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Bromide SCHEMBL27666738 0.98 ADRB1 (0.96) ADRB1DRD2DRD3HTR1AHTR3A
Hydrochloric Acid SCHEMBL2265022 0.96 ADRB1 (0.92) ADRB1DRD2DRD3HTR1AHTR3A
SCHEMBL3612685 0.92 ADRB1 (0.85) ADRB1DRD2DRD3HTR1AHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117925335-A Semiconductor titanium nitride cleaning solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2024-04-26 CN claimed
CN-117024376-A Preparation method of hydrobromic acid voltammetric acid duloxetine 寿光富康制药有限公司 2023-11-10 CN claimed
EP-4208177-A1 CELLULAR COMPOSITION FOR TREATMENT OF DISEASES, DISORDERS OR CONDITIONS AND METHOD OF USE Yztherapeutic Performance Ltd. (IL) 2023-07-12 EP claimed
CN-111886235-B Continuous process for preparing trazodone 方济各安吉利克化学联合股份有限公司 2023-06-30 CN claimed
CN-108473451-B Synthesis of 1- [2- (2, 4-dimethyl-phenylsulfanyl) -phenyl ] piperazine H.隆德贝克有限公司 2022-07-15 CN claimed
CN-109496211-B Piperazine derivative for resisting candida albicans as well as preparation method and application thereof 华南农业大学 2022-03-22 CN claimed
US-11261282-B2 PEO-PPO-PEO triblock bipolymers, with amphoteric endings, as demulsifying agents for heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2022-03-01 US claimed
US-20200347173-A1 PEO-PPO-PEO TRIBLOCK BIPOLYMERS, WITH AMPHOTERIC ENDINGS, AS DEMULSIFYING AGENTS FOR HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2020-11-05 US claimed
EP-3414231-B1 SYNTHESIS OF 1-[2-(2,4-DIMETHYL-PHENYLSULFANYL)-PHENYL]PIPERAZINE H LUNDBECK AS (DK) 2020-08-19 EP claimed
CN-108341807-B Piperazine amide compound containing benzodioxane skeleton and preparation method and application thereof 平顶山学院 2020-07-28 CN claimed
EP-1204677-A2 CYCLOHEXAPEPTIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS A PHARMACEUTICAL Aventis Pharma Deutschland GmbH (DE) 2002-05-15 EP claimed
US-6342251-B1 Compositions for nasal administration WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) 2002-01-29 US claimed
US-20010046519-A1 Compositions for nasal administration WEST PHARMACEUTICAL SERVICES DRUG DELIVERY 2001-11-29 US claimed
WO-2001007468-A2 NOVEL CYCLOHEXAPEPTIDE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS A PHARMACEUTICAL AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-02-01 WO claimed
EP-1035833-A1 COMPOSITIONS FOR NASAL ADMINISTRATION West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited (GB) 2000-09-20 EP claimed
WO-1999027905-A1 COMPOSITIONS FOR NASAL ADMINISTRATION WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) 1999-06-10 WO claimed
US-5788986-A Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression using R enantiomers, S enantiomers, and racemic mixtures of selective serotonin reuptake inhibitor compounds or their active metabolites TRUSTEES OF TUFTS COLLEGE (US) 1998-08-04 US claimed
EP-0853617-A1 NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES Novartis AG (CH) 1998-07-22 EP claimed
WO-1997008155-A1 NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES NOVARTIS AG (CH) 1997-03-06 WO claimed
EP-0539180-A1 Antiviral agents SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-04-28 EP claimed