Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 12/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 9/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978661 | 1.00 | GFER (0.53) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL23043645 | 0.83 | HTT (0.55) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL29978273 | 0.83 | HTT (0.55) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL23043647 | 0.81 | NR1I2 (0.46) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL29978338 | 0.81 | NR1I2 (0.46) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL23850826 | 0.80 | GFER (0.49) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL3485573 | 0.80 | GFER (0.49) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL3485570 | 0.80 | GFER (0.49) | GFERTP53MAPTPBRM1SMARCA2 | |
| SCHEMBL23043568 | 0.79 | PBRM1 (0.54) | GFERPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL29512584 | 0.79 | PBRM1 (0.54) | GFERPBRM1SMARCA2SMARCA4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |