SCHEMBL23043872

SCHEMBL23043872

C#CC[C@H](CO)CC#CCC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23125106 1.00 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL15967763 0.81
SCHEMBL23857370 0.80 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL3091986 0.75
SCHEMBL11507980 0.68
SCHEMBL4526347 0.67
SCHEMBL6084048 0.67
SCHEMBL13622369 0.67 GRIK1 (0.30) GRIK1GRIK2
SCHEMBL15654380 0.67 LMNA (0.65)
SCHEMBL27542665 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4021580-A1 CEREBLON E3 LIGASE INHIBITORS The Regents Of The University Of Michigan (US) 2022-07-06 EP disclosed
WO-2021041664-A1 CEREBLON E3 LIGASE INHIBITORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2021-03-04 WO disclosed