Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | NPY4R | P50391 | 8/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 6/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117141 | 0.95 | C3AR1 (0.40) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| SCHEMBL466294 | 0.95 | C3AR1 (0.40) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| SCHEMBL8164682 | 0.95 | C3AR1 (0.40) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| SCHEMBL27532875 | 0.90 | FOLH1 (0.41) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| SCHEMBL564120 | 0.90 | FOLH1 (0.41) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| Acetic Acid SCHEMBL1551710 | 0.87 | FOLH1 (0.39) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| Acetic Acid SCHEMBL160844 | 0.87 | FOLH1 (0.39) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| Acetic Acid SCHEMBL2170653 | 0.87 | FOLH1 (0.39) | FOLH1ITGB3ITGA2BC3AR1NOD1 | |
| SCHEMBL16260521 | 0.87 | NPY4R (0.38) | NPY4RNPY5RNPY1RNPY2RALOX15 | |
| Acetic Acid SCHEMBL28406175 | 0.86 | FOLH1 (0.48) | FOLH1C3AR1NOD1NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016065423-A1 | METHOD AND COMPOSITIONS FOR PREVENTING BACTERIAL CORROSION OF A SUBSTRATE | IXOM OPERATIONS PTY LTD (AU) | 2016-05-06 | — | — | WO | claimed |
| US-20150335663-A1 | Pharmaceutical Composition Having Synergistic Action Of Direct Catalase Inhibitors And Modulators Of NO Metabolism Or Of Extracellular Superoxide Anion Production Which Lead To Catalase Destruction | UNIVERSITAETSKLINIKUM FREIBURG (DE) | 2015-11-26 | — | — | US | claimed |
| EP-2863907-A1 | PHARMACEUTICAL COMPOSITION HAVING SYNERGISTIC ACTION OF DIRECT CATALASE INHIBITORS AND MODULATORS OF NO METABOLISM OR OF EXTRACELLULAR SUPEROXIDE ANION PRODUCTION WHICH LEAD TO CATALASE DESTRUCTION | Universitätsklinikum Freiburg (DE) | 2015-04-29 | — | — | EP | claimed |
| WO-2014001183-A1 | PHARMACEUTICAL COMPOSITION HAVING SYNERGISTIC ACTION OF DIRECT CATALASE INHIBITORS AND MODULATORS OF NO METABOLISM OR OF EXTRACELLULAR SUPEROXIDE ANION PRODUCTION WHICH LEAD TO CATALASE DESTRUCTION | Universitätsklinikum Freiburg (DE) | 2014-01-03 | — | — | WO | claimed |
| US-20050233944-A1 | Arginine compositions for coordinate modification of multiple cardiovascular risk factors | BABISH JOHN G | 2005-10-20 | — | — | US | claimed |
| US-20030054978-A1 | Arginine compositions for coordinate modification of multiple cardiovascular risk factors | METAPROTEOMICS, LLC | 2003-03-20 | — | — | US | claimed |
| WO-2003020260-A1 | ARGININE COMPOSITIONS FOR COORDINATE MODIFICATION OF MULTIPLE CARDIOVASCULAR RISK FACTORS | METAPROTEOMICS, LLC (US) | 2003-03-13 | — | — | WO | claimed |
| CN-112481337-B | High mannose glycoform content of regulatory ornithine metabolism to manipulate recombinant proteins | 美国安进公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112481337-A | Modulation of ornithine metabolism to manipulate high mannose glycoform content of recombinant proteins | 美国安进公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-106029896-B | Modulation of ornithine metabolism to manipulate high mannose glycoform content of recombinant proteins | 美国安进公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-105073757-B | Dyeing process using a hair-dyeing precursor obtained from an iridoid, composition, precursor and device comprising such a precursor | 莱雅公司 | 2019-12-17 | — | — | CN | disclosed |
| US-9801832-B2 | Pharmaceutical composition having synergistic action of direct catalase inhibitors and modulators of no metabolism or of extracellular superoxide anion production which lead to catalase destruction | UNIVERSITAETSKLINIKUM FREIBURG (DE) | 2017-10-31 | — | — | US | disclosed |
| EP-2351828-B1 | Methods and compositions for regulating biofilm development | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2017-10-18 | — | — | EP | disclosed |
| CN-101213292-A | Methods and compositions for modulating biofilm growth | ENVIRONMENTAL BIOTECHNOLOGY CR (AU) | 2008-07-02 | — | — | CN | disclosed |
| EP-1899451-A1 | METHODS AND COMPOSITIONS FOR REGULATING BIOFILM DEVELOPMENT | Environmental Biotechnology CRC Pty Limited (AU) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006125262-A1 | METHODS AND COMPOSITIONS FOR REGULATING BIOFILM DEVELOPMENT | ENVIRONMENTAL BIOTECHNOLOGY CRC PTY LIMITED (AU) | 2006-11-30 | — | — | WO | disclosed |
| US-7128930-B1 | Compositions and methods for treating sexual dysfunction | Sacks, Meir S. (US) | 2006-10-31 | — | — | US | disclosed |
| EP-1317309-B1 | COMPOSITIONS FOR TREATING SEXUAL DYSFUNCTION, CONTAINING AN NO-DONOR AND AN ANTIOXIDANT | SACKS MEIR S (US) | 2005-07-20 | — | — | EP | disclosed |
| EP-1317309-A2 | COMPOSITIONS FOR TREATING SEXUAL DYSFUNCTION, CONTAINING AN NO-DONOR AND AN ANTIOXIDANT | Sacks, Meir S. (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002019999-A2 | COMPOSITIONS FOR TREATING SEXUAL DYSFUNCTION, CONTAINING AN NO-DONOR AND AN ANTIOXIDANT | SACKS MEIR S (US) | 2002-03-14 | — | — | WO | disclosed |