SCHEMBL466294

SCHEMBL466294

N=C(N)NCCCC(NO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
C3AR1 Q16581 1/20 0.40
OTC P00480 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NOD1 Q9Y239 2/20 0.36
GNPAT O15228 1/20 0.36
FOLH1 Q04609 2/20 0.36
NPY4R P50391 7/20 0.35
NPY1R P25929 5/20 0.35
NPY5R Q15761 5/20 0.35
NPY2R P49146 3/20 0.35
DDAH1 O94760 1/20 0.33
GAA P10253 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117141 1.00 C3AR1 (0.40) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL8164682 1.00 C3AR1 (0.40) C3AR1OTCITGB3ITGA2BALOX15
Acetic Acid SCHEMBL2304560 0.95 FOLH1 (0.39) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL27532875 0.95 FOLH1 (0.41) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL564120 0.95 FOLH1 (0.41) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL30516542 0.89 TGFBR1 (0.33) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL1799746 0.87 NPY4R (0.39) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL29836396 0.87 ALOX15 (0.39) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL30068909 0.87 ALOX15 (0.39) C3AR1OTCITGB3ITGA2BALOX15
SCHEMBL1799745 0.87 NPY4R (0.39) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036541-A Amino acid-based ionizable lipid compound, and preparation method and application thereof 中国科学院广州生物医药与健康研究院 2026-05-15 CN claimed
CN-119780447-A Biomarker for early pregnancy related state of dairy cows and application thereof 宁夏大学 2025-04-08 CN claimed
EP-3463434-B1 IMMUNOTHERAPY FOR CANCER EXCOSO A S (CZ) 2024-12-25 EP claimed
CN-110508322-B Self-assembly nano material and preparation method and application thereof 国家纳米科学中心 2022-04-12 CN claimed
US-20210252120-A1 IMMUNOTHERAPY FOR CANCER SOTIO a.s. (CZ) 2021-08-19 US claimed
US-20190125850-A1 IMMUNOTHERAPY FOR CANCER SOTIO a.s. (CZ) 2019-05-02 US claimed
EP-3463434-A1 IMMUNOTHERAPY FOR CANCER Sotio a.s. (CZ) 2019-04-10 EP claimed
WO-2017211816-A1 IMMUNOTHERAPY FOR CANCER SOTIO a.s. (CZ) 2017-12-14 WO claimed
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US claimed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US claimed
WO-2003051825-A1 HUMAN ADAM-10 INHIBITORS EXELIXIS, INC. (US) 2003-06-26 WO claimed
EP-1185274-A1 DRUG COMBINATIONS COMPRISING (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO]PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND AN INHIBITOR, INDUCER OR SUBSTRATE OF P450 ISOENZYME 3A4 AstraZeneca AB (SE) 2002-03-13 EP claimed
CN-1338936-A Pharmaceutical composition comprising an inhibitor, inducer or substrate of -7- [ 4- (4-fluorophenyl) -6-isopropyl-2- [ methyl (methylsulfonyl) amino ] pyrimidin-5 yl ] (3R,5S) -3, 5-dihydroxyhept-6-enoic acid and P450 isozyme 3A4 ASTRAZENECA AB (SE) 2002-03-06 CN claimed
WO-2000045817-A1 DRUG COMBINATIONS COMPRISING (E) -7 - [4 -(4 -FLUOROPHENYL) -6 - ISOPROPYL -2 - [METHYL (METHYLSULFONYL) AMINO] PYRIMIDIN -5 -YL] (3R,5S) -3,5 - DIHYDROXYHEPT -6 - ENOIC ACID AND AN INHIBITOR, INDUCER OR SUBSTRATE OF P450 ISOENZYME 3A4 ASTRAZENECA AB (SE) 2000-08-10 WO claimed
EP-1012247-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING The Children's Medical Center Corporation (US) 2000-06-28 EP claimed
EP-0983346-A2 SHORT PEPTIDES WHICH SELECTIVELY MODULATE THE ACTIVITY OF SERINE/THREONINE KINASES The Children's Medical Center Corporation (US) 2000-03-08 EP claimed
WO-1999048923-A1 MULTIVALENT LIGANDS WHICH MODULATE ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1999-09-30 WO claimed
WO-1998053051-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO claimed
WO-1998053050-A2 SHORT PEPTIDES WHICH SELECTIVELY MODULATE THE ACTIVITY OF SERINE/THREONINE KINASES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO claimed
US-4847049-A Method of forming chelated collagen having bactericidal properties VITAPHORE CORPORATION (US) 1989-07-11 US claimed