SCHEMBL2304744

SCHEMBL2304744

CCOCC=O.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21495994 0.97
SCHEMBL21384945 0.97
SCHEMBL441144 0.97
SCHEMBL10431909 0.94
SCHEMBL108130 0.94
SCHEMBL9347264 0.94
SCHEMBL10822007 0.94
SCHEMBL9842273 0.94
SCHEMBL9747616 0.94
SCHEMBL9594852 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12071407-B1 6-(4-hydroxyphenyl)-2-(2-ethoxyethoxy)-4-(4-methoxyphenyl)nicotinonitrile as an antimicrobial compound King Faisal University (SA) 2024-08-27 US claimed
US-11970453-B1 2-ethoxy-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile as an antimicrobial compound King Faisal University (SA) 2024-04-30 US claimed
US-11926611-B1 2-(2-ethoxyethoxy)-6-phenyl-4,4′-bipyridine-3-carbonitrile as an antimicrobial compound King Faisal University (SA) 2024-03-12 US claimed
US-11926595-B1 2-(2-ethoxyethoxy)-6-(4-hydroxyphenyl)-4-(4-methylphenyl)nicotinonitrile as an antimicrobial compound King Faisal University (SA) 2024-03-12 US claimed
CN-110386881-A Diaryl ethylene compounds and its pharmaceutical composition and its application 中国科学院昆明植物研究所 2019-10-29 CN claimed
CN-107383035-B 2- ((1S3aR7aR) -5- tertbutyloxycarbonyl tetrahydrofuran simultaneously [3,4] piperidines -1) acetic acid preparation method 上海合全药业股份有限公司 2019-06-25 CN claimed
CN-109180721-A A kind of phenyl triethoxysilane preparation method 杨秀莲 2019-01-11 CN claimed
CN-109021006-A A kind of pollution-free method for preparing diphenyl diethoxy silane 杨秀莲 2018-12-18 CN claimed
US-12071407-B1 6-(4-hydroxyphenyl)-2-(2-ethoxyethoxy)-4-(4-methoxyphenyl)nicotinonitrile as an antimicrobial compound King Faisal University (SA) 2024-08-27 US disclosed
US-11926595-B1 2-(2-ethoxyethoxy)-6-(4-hydroxyphenyl)-4-(4-methylphenyl)nicotinonitrile as an antimicrobial compound King Faisal University (SA) 2024-03-12 US disclosed
US-11926611-B1 2-(2-ethoxyethoxy)-6-phenyl-4,4′-bipyridine-3-carbonitrile as an antimicrobial compound King Faisal University (SA) 2024-03-12 US disclosed
CN-110386881-A Diaryl ethylene compounds and its pharmaceutical composition and its application 中国科学院昆明植物研究所 2019-10-29 CN disclosed
CN-110204482-A A kind of preparation method of 4- pyridone -2,6- dicarboxylic acids 久泰能源(准格尔)有限公司 2019-09-06 CN disclosed
CN-109476760-A Anti- BASIGIN antibody of humanization and application thereof 中国人民解放军第四军医大学 2019-03-15 CN disclosed
WO-1987004810-A1 METHOD FOR DEVELOPING POLY(METHACRYLIC ANHYDRIDE) RESISTS HUGHES AIRCRAFT COMPANY (US) 1987-08-13 WO disclosed
US-4663420-A Polyetheroxy-substituted polyphosphazene purification ETHYL CORPORATION (US) 1987-05-05 US disclosed
US-4656246-A DISSOLVING, PRECIPITATION ETHYL CORPORATION (US) 1987-04-07 US disclosed
EP-0004730-B1 IMPROVEMENTS IN THE MANUFACTURE OF ALKYLSILICATES AND THEIR CONVERSION TO ALKYLPOLYSILICATES ZIRCONAL PROCESSES LIMITED (GB) 1982-11-10 EP disclosed
US-4211717-A REACTION OF SILICON AND ALCOHOL ZIRCONAL PROCESSES LIMITED (GB) 1980-07-08 US disclosed
EP-0004730-A2 Improvements in the manufacture of alkylsilicates and their conversion to alkylpolysilicates ZIRCONAL PROCESSES LIMITED (GB) 1979-10-17 EP disclosed