Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15353084 | 0.78 | TRPC6 (0.41) | TRPC6 | |
| SCHEMBL30621938 | 0.78 | TRPC6 (0.41) | TRPC6 | |
| SCHEMBL609450 | 0.78 | TRPC6 (0.46) | TRPC6 | |
| SCHEMBL21045776 | 0.76 | TRPC6 (0.54) | TRPC6 | |
| SCHEMBL29817980 | 0.75 | BACE1 (0.43) | TRPC6 | |
| SCHEMBL13490639 | 0.75 | MTOR (0.40) | — | |
| SCHEMBL13490675 | 0.74 | TLR8 (0.35) | — | |
| SCHEMBL29818263 | 0.73 | BACE1 (0.46) | TRPC6 | |
| SCHEMBL21285985 | 0.73 | SLC18A3 (0.49) | — | |
| SCHEMBL21288632 | 0.71 | TRPC6 (0.41) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786160-A1 | PYRIDINE DERIVATIVES AND THERAPEUTIC USES THEREOF AS TRPC6 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2021-03-03 | — | — | EP | disclosed |