Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 8/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22393557 | 0.94 | CYP3A4 (0.36) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL22355553 | 0.94 | CYP3A4 (0.36) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL22393558 | 0.93 | CYP3A4 (0.44) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL22393430 | 0.93 | CYP3A4 (0.44) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL22392915 | 0.93 | BTN3A1 (0.37) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL24058364 | 0.92 | CYP3A4 (0.36) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL26294375 | 0.91 | CYP3A4 (0.34) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL24158211 | 0.87 | DOT1L (0.34) | RIPK1 | |
| SCHEMBL26293675 | 0.86 | BTN3A1 (0.34) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL22355532 | 0.85 | BTN3A1 (0.34) | CYP3A4CYP2C9BTN3A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |