Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29711913 | 1.00 | PDE4D (0.52) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL7564025 | 0.91 | BCHE (0.50) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL7564019 | 0.91 | BCHE (0.50) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL7570831 | 0.84 | PDE4D (0.57) | PDE4DBCHEACHESLC6A2GJB2 | |
| SCHEMBL7570823 | 0.84 | PDE4D (0.57) | PDE4DBCHEACHESLC6A2GJB2 | |
| SCHEMBL7570826 | 0.84 | PDE4D (0.57) | PDE4DBCHEACHESLC6A2GJB2 | |
| SCHEMBL459736 | 0.84 | LMNA (0.48) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL28660614 | 0.81 | LMNA (0.46) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL18699903 | 0.81 | LMNA (0.46) | PDE4DBCHEACHELMNADRD1 | |
| SCHEMBL7570125 | 0.80 | BCHE (0.50) | PDE4DBCHEACHELMNADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |