Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808519 | 0.87 | NPSR1 (0.61) | PDE3BPDE3ANPSR1TSHRALDH1A1 | |
| SCHEMBL5882460 | 0.83 | PDE4D (0.52) | PDE3BPDE3AHMGCRCYP3A4PDE4D | |
| SCHEMBL14531013 | 0.79 | NPSR1 (0.52) | PDE3BPDE3ANPSR1HMGCRCYP3A4 | |
| SCHEMBL5883035 | 0.79 | ALDH1A1 (0.49) | PDE3BPDE3AHMGCRCYP3A4PDE4D | |
| SCHEMBL2429736 | 0.79 | CYP4F2 (0.49) | NPSR1TAAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9540619 | 0.78 | ELANE (0.39) | PDE3BPDE3ANPSR1HMGCRCYP3A4 | |
| SCHEMBL2473673 | 0.78 | NPSR1 (0.50) | PDE3BPDE3ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL19006513 | 0.77 | MAPT (0.50) | PDE3BPDE3APDE4DALDH1A1 | |
| SCHEMBL63388 | 0.77 | KMT2A (0.55) | ALDH1A1 | |
| SCHEMBL9296450 | 0.76 | PDE4D (0.45) | PDE3BPDE3AHMGCRCYP3A4PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284736-B1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2021-03-03 | — | — | EP | disclosed |