Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | IL18 | Q14116 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214039 | 0.90 | CYP3A4 (0.43) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL13828465 | 0.90 | CYP3A4 (0.43) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL13828462 | 0.90 | CYP3A4 (0.43) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL13828464 | 0.87 | SAE1 (0.43) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL19216513 | 0.83 | SAE1 (0.64) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL19214036 | 0.81 | SAE1 (0.50) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL14668125 | 0.80 | TSHR (0.56) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL19043004 | 0.79 | SAE1 (0.55) | SAE1UBA2MAPTLMNAPOLB | |
| SCHEMBL21573535 | 0.77 | SAE1 (0.78) | SAE1UBA2MAPTLMNAMEN1 | |
| SCHEMBL18844746 | 0.75 | HPGD (0.57) | SAE1UBA2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513183-B1 | FLAME RETARDANT POLYURETHANE FOAMS CONTAINING BIURET LINKAGES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-03-03 | — | — | EP | disclosed |