SCHEMBL18844746

SCHEMBL18844746

CC(C)OC(=O)Nc1ccc(Cc2ccc(OC#N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.57
RAB9A P51151 2/20 0.57
NPC1 O15118 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SAE1 Q9UBE0 2/20 0.47
UBA2 Q9UBT2 2/20 0.47
KDM4E B2RXH2 1/20 0.45
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP14 P50281 1/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19043004 0.86 SAE1 (0.55) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL5023024 0.86 HPGD (0.65) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL14668125 0.82 TSHR (0.56) HPGDRAB9ACYP1A2CYP2C9CYP2C19
SCHEMBL23943707 0.82 SAE1 (0.42) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL19216513 0.82 SAE1 (0.64) RAB9ANPC1SMN1; SMN2SAE1UBA2
SCHEMBL22199107 0.81 SAE1 (0.40) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL19214036 0.80 SAE1 (0.50) HPGDRAB9ASMN1; SMN2SAE1UBA2
SCHEMBL4238001 0.79 RAB9A (0.56) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL20718615 0.79 HPGD (0.56) HPGDRAB9ANPC1CYP1A2CYP2D6
SCHEMBL18804818 0.79 HPGD (0.56) HPGDRAB9ANPC1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4018870-B1 COMPONENTS OF ARTICLES OF FOOTWEAR, AND PROCESSES FOR MAKING ARTICLES OF FOOTWEAR OR COMPONENTS THEREOF NIKE INNOVATE CV (US) 2024-07-03 EP disclosed
US-20240067826-A1 COLORANT SOLVENT SYSTEM, METHODS OF USE, AND ARTICLES NIKE, INC. 2024-02-29 US disclosed
US-20240065373-A1 SOLE STRUCTURES INCLUDING POLYOLEFIN PLATES AND ARTICLES OF FOOTWEAR FORMED THEREFROM NIKE, INC. 2024-02-29 US disclosed
US-20230366078-A1 STRUCTURALLY-COLORED ARTICLES AND METHODS FOR MAKING AND USING STRUCTURALLY-COLORED ARTICLES NIKE, INC. 2023-11-16 US disclosed
US-11786007-B2 Layered materials, methods of making, methods of use, and articles incorporation the layered materials NIKE, INC. (US) 2023-10-17 US disclosed
US-20230284738-A1 ARTICLES AND METHODS OF MAKING ARTICLES INCLUDING A COATING NIKE, INC. 2023-09-14 US disclosed
US-20230276898-A1 ARTICLES INCLUDING COATED FIBERS AND METHODS OF MAKING COATED FIBERS AND ARTICLES NIKE, INC. 2023-09-07 US disclosed
US-20230272215-A1 MULTI-LAYERED STRUCTURES AND USES THEREOF NIKE, INC. 2023-08-31 US disclosed
US-11733430-B2 2023-08-22 US disclosed
US-11685831-B2 Filled polymeric resin materials and methods of making NIKE, INC. (US) 2023-06-27 US disclosed
US-20190098958-A1 STRUCTURALLY-COLORED ARTICLES AND METHODS FOR MAKING AND USING STRUCTURALLY-COLORED ARTICLES NIKE, INC. 2019-04-04 US disclosed
US-20190099979-A1 STRUCTURALLY-COLORED ARTICLES AND METHODS FOR MAKING AND USING STRUCTURALLY-COLORED ARTICLES NIKE, INC. 2019-04-04 US disclosed
US-20190039342-A1 METHOD OF MANUFACTURING A COMPONENT OF AN OUTSOLE FOR USE IN AN ARTICLE OF FOOTWEAR NIKE, INC. 2019-02-07 US disclosed
US-20180127904-A1 KNIT TEXTILES AND UPPERS, AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2018-05-10 US disclosed
US-20180125165-A1 TEXTILES AND ARTICLES, AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2018-05-10 US disclosed
US-20170251759-A1 HYDROGEL CONNECTION NIKE, INC. (US) 2017-09-07 US disclosed
US-20170251752-A1 HYDROGEL WITH MESH FOR SOIL DEFLECTION NIKE, INC. (US) 2017-09-07 US disclosed
US-20170252722-A1 ARTICLES WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. (US) 2017-09-07 US disclosed
US-20170238653-A1 ARTICLES OF FOOTWEAR, APPAREL, AND SPORTS EQUIPMENT WITH SOIL-SHEDDING PROPERTIES NIKE, INC. (US) 2017-08-24 US disclosed
US-20170129200-A1 ARTICLES OF WEAR AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2017-05-11 US disclosed