⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701399 | 0.80 | GAA (0.39) | — | |
| SCHEMBL9965198 | 0.79 | GAA (0.42) | — | |
| SCHEMBL452395 | 0.77 | — | — | |
| SCHEMBL15538351 | 0.77 | — | — | |
| SCHEMBL13518716 | 0.75 | — | — | |
| SCHEMBL29791687 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL503237 | 0.72 | — | — | |
| SCHEMBL17796888 | 0.70 | — | — | |
| SCHEMBL29791684 | 0.69 | GAA (0.42) | — | |
| SCHEMBL700675 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071432-A | Synthesis method of fluoro spiro quinolinone derivative | 淮南师范学院 | 2026-05-22 | — | — | CN | claimed |
| CN-119930486-A | Para-toluenesulfonyl modified difluoro acetonitrile precursor compound, and synthetic method and application thereof | 平顶山学院 | 2025-05-06 | — | — | CN | claimed |
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119285424-A | Method for synthesizing alpha-aryl ketone compound from aryl allylic amide | 福州大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119080701-A | Synthesis method of imidazole difluoromethylation reaction promoted by alkali | 西安工程大学 | 2024-12-06 | — | — | CN | claimed |
| CN-116334840-B | Double-layer composite fiber material and preparation method thereof | 扬州阿特兰新材料有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | claimed |
| CN-117645564-A | Fluoroalkyl substituted indole derivative and synthetic method and application thereof | 齐鲁工业大学(山东省科学院) | 2024-03-05 | — | — | CN | claimed |
| CN-114539107-B | Aromatic sulfonyl modified difluoromethyl reaction building block and synthesis method thereof | 平顶山学院 | 2023-09-15 | — | — | CN | claimed |
| CN-114959750-B | Method for preparing (E) -2, 2-difluoro-4-phenylbut-3-ethyl enoate compound by electrocatalytic | 上海第二工业大学 | 2023-09-01 | — | — | CN | claimed |
| CN-116478064-A | 2-azido-2, 2-difluoro-N-aryl acetamide and synthesis method and application thereof | 平顶山学院 | 2023-07-25 | — | — | CN | claimed |
| CN-116334840-A | Double-layer composite fiber material and preparation method thereof | 扬州阿特兰新材料有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-113173852-A | Preparation method of difluoro malonate type compound | 深圳市华先医药科技有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-108774147-B | N-aryl formamide prepared by taking bromodifluoroacetic acid ethyl ester as formylation reagent | 温州大学 | 2021-01-08 | — | — | CN | claimed |
| CN-122071432-A | Synthesis method of fluoro spiro quinolinone derivative | 淮南师范学院 | 2026-05-22 | — | — | CN | disclosed |
| CN-121574075-A | Photoacid generator Synthesis method of intermediate | 苏州源起材料科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-121574075-A | Photoacid generator Synthesis method of intermediate | 苏州源起材料科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-5389647-A | A prodrugs as hypotensive agents, treating congestive heart failure, urogenital disorders, vision defects | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |
| US-5244910-A | Treating hypertension, congestive heart failure | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0504064-A1 | Novel thrombin inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1992-09-16 | — | — | EP | disclosed |