Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735722 | 0.89 | APLNR (0.58) | APLNR | |
| SCHEMBL21073165 | 0.88 | APLNR (0.75) | APLNR | |
| SCHEMBL21073517 | 0.86 | APLNR (0.76) | APLNR | |
| SCHEMBL21073842 | 0.86 | APLNR (0.76) | APLNR | |
| SCHEMBL21073051 | 0.86 | APLNR (0.76) | APLNR | |
| SCHEMBL19717937 | 0.85 | APLNR (0.64) | APLNR | |
| SCHEMBL21072952 | 0.85 | APLNR (0.77) | APLNR | |
| SCHEMBL21073211 | 0.84 | APLNR (0.77) | APLNR | |
| SCHEMBL19717898 | 0.84 | APLNR (0.60) | APLNR | |
| SCHEMBL21073682 | 0.83 | APLNR (0.77) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |