Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25440195 | 0.84 | EPHX1 (0.43) | EPHX1ACACB | |
| SCHEMBL25440118 | 0.84 | EPHX1 (0.43) | EPHX1ACACB | |
| SCHEMBL7272253 | 0.83 | MGAM (0.40) | EPHX1ACACB | |
| SCHEMBL3463291 | 0.82 | EPHX1 (0.41) | EPHX1ACACBCYP2C19 | |
| SCHEMBL16244250 | 0.80 | EPHX1 (0.43) | EPHX1IRAK4ACACBCYP2C19 | |
| SCHEMBL12987206 | 0.79 | EPHX1 (0.46) | EPHX1IRAK4ACACB | |
| SCHEMBL25440196 | 0.79 | EPHX1 (0.39) | EPHX1ACACB | |
| SCHEMBL26330128 | 0.79 | EPHX1 (0.39) | EPHX1ACACB | |
| SCHEMBL5365449 | 0.79 | ALDH1A1 (0.40) | EPHX1 | |
| SCHEMBL10071411 | 0.79 | EPHX1 (0.39) | EPHX1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596064-B1 | TOSYLACETATE BASED COMPOUNDS AND DERIVATIVES THEREOF AS PHGDH INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-03 | — | — | EP | disclosed |