Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598370 | 0.82 | KDM4E (0.47) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11107810 | 0.81 | KDM4E (0.54) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11212338 | 0.81 | KDM4E (0.60) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11166036 | 0.80 | KDM4E (0.53) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9318527 | 0.79 | KDM4E (0.45) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9878668 | 0.79 | KDM4E (0.47) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11160106 | 0.78 | KDM4E (0.53) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11165433 | 0.78 | KDM4E (0.51) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11165430 | 0.78 | KDM4E (0.51) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11160112 | 0.78 | KDM4E (0.53) | KDM4ELMNAESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11385229-B2 | Amplification technology using dual enzyme cascade detection | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-09 | — | — | US | disclosed |
| WO-2021041583-A1 | COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | GUSB, GLB1, MGAM | KDM4E 2730/4885LMNA 403/4885ESR1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.