Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051170 | 0.79 | KDM4E (0.50) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11590192 | 0.76 | KDM4E (0.43) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11107810 | 0.76 | KDM4E (0.54) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11212338 | 0.75 | KDM4E (0.60) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL5344466 | 0.75 | KDM4E (0.43) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9596535 | 0.74 | KDM4E (0.52) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9696917 | 0.74 | KDM4E (0.53) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9318527 | 0.74 | KDM4E (0.45) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL16274079 | 0.73 | KDM4E (0.51) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11130125 | 0.73 | KDM4E (0.51) | KDM4ELMNAESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |