⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1204323 | 0.73 | USP2 (0.41) | — | |
| SCHEMBL1193790 | 0.73 | ALDH1A1 (0.33) | — | |
| Methyl Carbamate SCHEMBL28068168 | 0.71 | CA14 (0.40) | — | |
| SCHEMBL4742771 | 0.71 | — | — | |
| SCHEMBL1947040 | 0.71 | — | — | |
| SCHEMBL7692952 | 0.71 | — | — | |
| SCHEMBL577100 | 0.71 | — | — | |
| SCHEMBL21816739 | 0.71 | — | — | |
| SCHEMBL27483727 | 0.71 | — | — | |
| SCHEMBL8705575 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-101801935-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2014-12-03 | — | — | CN | claimed |
| CN-1044117-C | Inhibitors of HIV protease useful for the treatment of aids | LILLY CO ELI (US) | 1999-07-14 | — | — | CN | claimed |
| CN-1094399-A | Inhibitors of HIV protease as the treatment AIDS | LILLY CO ELI (US) | 1994-11-02 | — | — | CN | claimed |
| CN-113195441-B | Androgen receptor modulators and methods of use thereof | 埃萨制药股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118005640-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114380825-B | Substituted pyrazole condensed ring derivative and preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-111918651-B | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116997547-A | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-113490670-B | Nitrogen-containing polycyclic condensed ring compound, pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |
| CN-1665809-A | Azaindoles | AVENTIS PHARMA LTD (GB) | 2005-09-07 | — | — | CN | disclosed |
| EP-0732338-B1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | LILLY CO ELI (US) | 2002-05-15 | — | — | EP | disclosed |
| CN-1340050-A | Heterocyclic benzenesulphonamide compounds as bradykinine antagonists | FOURNIER IND & SANTE (FR) | 2002-03-13 | — | — | CN | disclosed |
| CN-1044117-C | Inhibitors of HIV protease useful for the treatment of aids | LILLY CO ELI (US) | 1999-07-14 | — | — | CN | disclosed |
| EP-0732338-A1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5521294-A | 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| CN-1094399-A | Inhibitors of HIV protease as the treatment AIDS | LILLY CO ELI (US) | 1994-11-02 | — | — | CN | disclosed |