Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.35 |
| ▸ | ALPP | P05187 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052208 | 0.93 | MME (0.39) | MMEMMEL1PRKD1ALPPTAS1R3 | |
| SCHEMBL23052249 | 0.90 | MMP13 (0.36) | MMEPRKD1ALPPALDH1A1MAPT | |
| SCHEMBL23052178 | 0.89 | GAA (0.39) | MMEMAPTGAA | |
| SCHEMBL23042188 | 0.88 | PRKD1 (0.36) | MMEMMEL1PRKD1ALPP | |
| SCHEMBL23051928 | 0.88 | MME (0.40) | MMEMMEL1PRKD1ALPP | |
| SCHEMBL29707769 | 0.88 | MME (0.40) | MMEMMEL1PRKD1ALPP | |
| SCHEMBL23051931 | 0.88 | MME (0.40) | MMEMMEL1PRKD1ALPP | |
| SCHEMBL23041487 | 0.86 | MME (0.44) | MMEMMEL1PRKD1SMN1; SMN2TAS1R3 | |
| SCHEMBL23041640 | 0.86 | MME (0.45) | MMEMMEL1ALPP | |
| SCHEMBL29452352 | 0.86 | MME (0.44) | MMEMMEL1PRKD1SMN1; SMN2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |