Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 11/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | ALPP | P05187 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707865 | 0.94 | PRKD1 (0.38) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL29707801 | 0.94 | PRKD1 (0.38) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL23041527 | 0.94 | PRKD1 (0.38) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL23041699 | 0.94 | PRKD1 (0.38) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL23041519 | 0.94 | PRKD1 (0.38) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL28724388 | 0.92 | PRKD1 (0.37) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL29452642 | 0.92 | PRKD1 (0.37) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL28724377 | 0.92 | PRKD1 (0.37) | PRKD1MMESMYD3ALPPMAPT | |
| SCHEMBL29707750 | 0.88 | KMT2A (0.42) | PRKD1 | |
| SCHEMBL23041520 | 0.88 | PRKD1 (0.38) | PRKD1MMESMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |