Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041604 | 0.89 | KMT2A (0.40) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23041632 | 0.89 | KMT2A (0.40) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL28721826 | 0.89 | KMT2A (0.40) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23041634 | 0.89 | KMT2A (0.40) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23051909 | 0.89 | KMT2A (0.40) | KMT2AMEN1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23051994 | 0.88 | PRKD1 (0.37) | PRKD1 | |
| SCHEMBL23041699 | 0.82 | PRKD1 (0.38) | PRKD1 | |
| SCHEMBL23041519 | 0.82 | PRKD1 (0.38) | PRKD1 | |
| SCHEMBL23041527 | 0.82 | PRKD1 (0.38) | PRKD1 | |
| SCHEMBL29707801 | 0.82 | PRKD1 (0.38) | PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021572-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Novartis AG (CH) | 2022-07-06 | — | — | EP | disclosed |