Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052401 | 1.00 | KMT2A (1.00) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL3314124 | 0.84 | KMT2A (0.71) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL23052565 | 0.78 | MAPT (1.00) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL23052501 | 0.77 | KMT2A (0.65) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL9649368 | 0.75 | MAOB (0.69) | KMT2AMEN1MAPTALDH1A1MAOB | |
| SCHEMBL23052500 | 0.75 | KMT2A (0.65) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL27918012 | 0.75 | MAOB (0.64) | KMT2AMEN1MAOBMAOALMNA | |
| SCHEMBL23052112 | 0.74 | KMT2A (0.71) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL23052547 | 0.72 | KMT2A (1.00) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL23052092 | 0.72 | LMNA (0.78) | KMT2AMEN1MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |