Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052324 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052455 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052499 | 0.90 | MEN1 (0.74) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052564 | 0.90 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052435 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052194 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052355 | 0.88 | KMT2A (0.86) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3315214 | 0.87 | KDM4E (0.66) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052357 | 0.86 | MEN1 (0.84) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23052562 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |