Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | TERT | O14746 | 11/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052333 | 0.91 | POLB (0.54) | ACHETERTPOLBMEN1KMT2A | |
| SCHEMBL23052323 | 0.83 | ACHE (0.71) | ACHETERTMEN1KMT2ACYP1A2 | |
| SCHEMBL23052151 | 0.83 | ACHE (0.71) | ACHETERTMEN1KMT2ACYP1A2 | |
| SCHEMBL14659832 | 0.76 | KMT2A (0.69) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1660270 | 0.75 | ACHE (0.92) | ACHETERTMEN1KMT2ACYP1A2 | |
| SCHEMBL31574583 | 0.70 | MEN1 (0.57) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL23052325 | 0.70 | MEN1 (0.69) | TERTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL31574531 | 0.70 | KMT2A (0.59) | ACHEPOLBMEN1KMT2ACYP1A2 | |
| SCHEMBL23052332 | 0.69 | KMT2A (0.73) | ACHETERTMEN1KMT2ACYP1A2 | |
| SCHEMBL31574522 | 0.68 | MEN1 (0.59) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |