Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452797 | 1.00 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL23052268 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL29452759 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL23052251 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL23052252 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL23052269 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBMMEHSP90AA1F11 | |
| SCHEMBL23051954 | 0.93 | TACR3 (0.34) | POLBMMEHSP90AA1ALDH1A1ACACB | |
| SCHEMBL29452820 | 0.93 | TACR3 (0.34) | POLBMMEHSP90AA1ALDH1A1ACACB | |
| SCHEMBL23051952 | 0.93 | TACR3 (0.34) | POLBMMEHSP90AA1ALDH1A1ACACB | |
| SCHEMBL23041511 | 0.90 | MME (0.38) | SLC8A1MMEMMEL1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |