Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452759 | 1.00 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1SMYD3MME | |
| SCHEMBL23052268 | 1.00 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1SMYD3MME | |
| SCHEMBL23052269 | 1.00 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1SMYD3MME | |
| SCHEMBL23052252 | 1.00 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1SMYD3MME | |
| SCHEMBL29452797 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1MMEALDH1A1 | |
| SCHEMBL23052246 | 0.94 | SLC8A1 (0.36) | SLC8A1POLBHSP90AA1MMEALDH1A1 | |
| SCHEMBL23052262 | 0.93 | TACR3 (0.34) | POLBHSP90AA1SMYD3MMEALDH1A1 | |
| SCHEMBL29452761 | 0.93 | TACR3 (0.34) | POLBHSP90AA1SMYD3MMEALDH1A1 | |
| SCHEMBL23052264 | 0.93 | TACR3 (0.34) | POLBHSP90AA1SMYD3MMEALDH1A1 | |
| SCHEMBL28722803 | 0.93 | TACR3 (0.34) | POLBHSP90AA1SMYD3MMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |