Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862841 | 0.90 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2304685 | 0.84 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2302834 | 0.83 | TSHR (0.46) | TSHRHPGDATMPPARDHCAR2 | |
| SCHEMBL17923891 | 0.83 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17350475 | 0.82 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL24549756 | 0.82 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3212690 | 0.81 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL978404 | 0.80 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28248035 | 0.80 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21219376 | 0.79 | TSHR (0.52) | TSHRALDH1A1CYP3A4PPARDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372516-B2 | (Meth)acrylate phosphonic esters as adhesion promoters | BASF SE (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2350215-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100112362-A1 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | CIBA CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010049322-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |