Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212690 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL978404 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2305261 | 0.84 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28016171 | 0.83 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2304758 | 0.82 | ATM (0.46) | TSHRHPGDPPARDATMHCAR2 | |
| SCHEMBL24549756 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2303000 | 0.80 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL16862841 | 0.80 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Triethyl Phosphate SCHEMBL28788446 | 0.80 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL9644675 | 0.79 | ALDH1A1 (0.52) | TSHRALDH1A1PPARDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342744-B2 | Compositions with controlled network structure | IVOCLAR VIVADENT AG (LI) | 2019-07-09 | — | — | US | disclosed |
| US-20170172855-A1 | Compositions With Controlled Network Structure | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-22 | — | — | US | disclosed |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-08 | — | — | US | disclosed |
| EP-3166568-A1 | DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES | Ivoclar Vivadent AG (LI) | 2017-05-17 | — | — | EP | disclosed |
| EP-3166569-A1 | COMPOSITES HAVING A CONTROLLED NETWORK STRUCTURE | Ivoclar Vivadent AG (LI) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005540-A1 | DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016005534-A1 | COMPOSITES HAVING A CONTROLLED NETWORK STRUCTURE | IVOCLAR VIVADENT AG (LI) | 2016-01-14 | — | — | WO | disclosed |
| EP-2965740-A1 | Dental materials with debonding on demand properties | Ivoclar Vivadent AG (LI) | 2016-01-13 | — | — | EP | disclosed |
| EP-2965741-A1 | Composites with controlled network structure | Ivoclar Vivadent AG (LI) | 2016-01-13 | — | — | EP | disclosed |
| US-8372516-B2 | (Meth)acrylate phosphonic esters as adhesion promoters | BASF SE (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2350215-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100112362-A1 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | CIBA CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010049322-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172855-A1 | Compositions With Controlled Network Structure | NCLN, RAD51, SMCHD1 | TSHR 4627/4885HPGD 19/4885ALDH1A1 2901/4885 |
| US-10342744-B2 | Compositions with controlled network structure | NCLN, RAD51, SMCHD1 | TSHR 4627/4885HPGD 19/4885ALDH1A1 2901/4885 |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | DCLRE1A, RAD51, TERB1 | TSHR 3799/4885HPGD 309/4885ALDH1A1 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.