SCHEMBL230537

SCHEMBL230537

C=CC(=O)OCCC[Si](OCCOC)(OCCOC)OCCOC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.51
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798540 0.95 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6151294 0.95 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11059699 0.87 TSHR (0.40) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL229125 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL231020 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL949700 0.85 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL93193 0.84 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL136294 0.84 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL93561 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL71730 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO claimed
CN-113956727-B Colorant composition and coated article 广东华润涂料有限公司 2023-02-17 CN claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
CN-113956727-A Colorant composition and coated article 广东华润涂料有限公司 2022-01-21 CN claimed
EP-3049483-B1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2019-06-12 EP claimed
US-10035915-B2 Low refractive index coating for optical fibers, methods of manufacture thereof and articles comprising the same OFS FITEL, LLC (US) 2018-07-31 US claimed
US-20160369103-A1 LOW REFRACTIVE INDEX COATING FOR OPTICAL FIBERS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME OFS FITEL LLC (US) 2016-12-22 US claimed
US-20160244615-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2016-08-25 US claimed
US-20100190637-A1 Curing Catalyst MERCK PATENT GESELLSCHAFT (DE) 2010-07-29 US claimed
EP-2160239-A1 CURING CATALYST Merck Patent GmbH (DE) 2010-03-10 EP claimed
WO-2009015713-A1 CURING ACCELERATOR MERCK PATENT GMBH (DE) 2009-02-05 WO claimed
WO-2009000378-A1 CURING CATALYST MERCK PATENT GMBH (DE) 2008-12-31 WO claimed
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 US claimed
EP-1721731-A1 Layered structure, method of its preparation and use Celanese Emulsions GmbH (DE) 2006-11-15 EP claimed
US-4448848-A Magnetic recording medium and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US claimed
US-4076890-A SILANE COUPLING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
EP-3999019-B1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A COATED EFFECT PIGMENT AND A FILM-FORMING POLYMER II HENKEL AG & CO KGAA (DE) 2026-05-06 EP disclosed
EP-0073064-A1 Filled organic polymeric compositions and a mixture for preparing said compositions UNION CARBIDE CORPORATION (US) 1983-03-02 EP disclosed
US-4100127-A Process for preparation of grafted unsaturated polyester liquid resin dispersion KAO SOAP CO., LTD. (JP) 1978-07-11 US disclosed