SCHEMBL93193

SCHEMBL93193

C=CC(=O)OCCC[Si](OCCOCC)(OCCOCC)OCCOCC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 5/20 0.49
TP53 P04637 3/20 0.49
HIF1A Q16665 3/20 0.49
CYP3A4 P08684 2/20 0.49
HSD17B10 Q99714 1/20 0.49
THRB P10828 3/20 0.45
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3041892 0.88 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL93561 0.87 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10798540 0.87 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A
Hydrogen Peroxide SCHEMBL28128571 0.86 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2220386 0.86 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL949700 0.86 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4249650 0.85 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL970916 0.85 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL230537 0.84 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL136294 0.84 TSHR (0.71) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862806-B2 Plastic article for automotive glazing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2607413-B1 Plastic Substrate for Automotive Glazing and Its Repairing Method SHINETSU CHEMICAL CO (JP) 2017-06-21 EP disclosed
EP-2426175-B1 Plastic article for automotive glazing SHINETSU CHEMICAL CO (JP) 2014-07-23 EP disclosed
US-20130164539-A1 PLASTIC SUBSTRATE FOR AUTOMOTIVE GLAZING AND ITS REPAIRING METHOD KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-06-27 US disclosed
EP-2607413-A1 Plastic Substrate for Automotive Glazing and Its Repairing Method Shin-Etsu Chemical Co., Ltd. (JP) 2013-06-26 EP disclosed
US-20120058347-A1 PLASTIC ARTICLE FOR AUTOMOTIVE GLAZING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
EP-2426175-A1 Plastic article for automotive glazing Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-07 EP disclosed
EP-0822240-B1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS LTD (JP) 2002-09-25 EP disclosed
US-6329456-B1 FOR FORMING A COATING FILM OF HIGH HARDNESS, HEAT RESISTANCE AND WEATHERABILITY MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2001-12-11 US disclosed
US-6090873-A ACRYLATE TERPOLYMER CONTAINING EPOXY AND ALKOXYSILANE GROUPS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2000-07-18 US disclosed
EP-0822240-A1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1998-02-04 EP disclosed