Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599399 | 0.84 | EPHX1 (0.71) | P4HTMEPHX1CYP1A2SRRCYP2C19 | |
| SCHEMBL3079795 | 0.84 | EPHX1 (0.71) | P4HTMEPHX1CYP1A2SRRCYP2C19 | |
| SCHEMBL67234 | 0.84 | EPHX1 (0.71) | P4HTMEPHX1CYP1A2SRRCYP2C19 | |
| Hydrochloric Acid SCHEMBL933353 | 0.82 | EPHX1 (0.69) | P4HTMEPHX1CYP1A2SRRCYP2C19 | |
| SCHEMBL6201202 | 0.81 | ALDH1A1 (0.46) | EPHX1CYP1A2SRRPTGS1ALPI | |
| SCHEMBL5156210 | 0.81 | ESR1 (0.61) | P4HTMEPHX1CYP1A2PTGS1ALPI | |
| SCHEMBL4153500 | 0.79 | P4HTM (0.56) | P4HTMEPHX1CYP1A2SRRCYP2C19 | |
| SCHEMBL1150918 | 0.79 | EPHX1 (0.61) | P4HTMEPHX1CYP1A2SRRPTGS1 | |
| SCHEMBL22070724 | 0.79 | P4HTM (0.56) | P4HTMEPHX1CYP1A2PTGS1ALPI | |
| SCHEMBL29152992 | 0.79 | P4HTM (0.56) | P4HTMEPHX1CYP1A2CYP2C19PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | RADIUS HEALTH, INC. | 2012-01-05 | — | — | US | disclosed |
| US-7960412-B2 | Selective estrogen receptor modulator | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | ESR1, GPER1, ESR2 | P4HTM 1596/4885EPHX1 1361/4885CYP1A2 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.