Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244013 | 0.81 | HDAC1 (0.58) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL15482200 | 0.80 | HDAC1 (0.64) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL17483891 | 0.79 | HDAC1 (0.71) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL13949861 | 0.76 | HDAC1 (0.69) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL12592142 | 0.76 | HDAC3 (0.71) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL16088850 | 0.73 | SMN1; SMN2 (0.62) | KMT2AALDH1A1MAPT | |
| SCHEMBL23054865 | 0.73 | HDAC3 (0.75) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL17483934 | 0.73 | HDAC6 (0.65) | HDAC3HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL9480955 | 0.72 | ALDH1A1 (0.49) | KCNH2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8235166 | 0.72 | HDAC1 (0.65) | HDAC3HDAC6HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | HDAC3 1/4885HDAC6 10/4885HDAC1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.