Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 3/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055097 | 0.88 | MAPT (0.59) | KDM4EALDH1A1MAPTHSD17B10GFER | |
| SCHEMBL23054961 | 0.84 | DRD4 (0.59) | CACNA1GDRD4HDAC1HDAC3HDAC4 | |
| SCHEMBL27459405 | 0.83 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL8246835 | 0.81 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL8744966 | 0.81 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL8745027 | 0.80 | KDM4E (0.70) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL7251471 | 0.79 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL23054969 | 0.79 | MAPK1 (0.63) | KDM4ESMN1; SMN2LMNADRD4DRD2 | |
| Hydrochloric Acid SCHEMBL8745028 | 0.79 | KDM4E (0.68) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL6031705 | 0.79 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | KDM4E 330/4885SMN1; SMN2 2901/4885ALDH1A1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.