Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.60 |
| ▸ | GFER | P55789 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8745027 | 0.99 | KDM4E (0.70) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL8744975 | 0.86 | ITGB3 (0.64) | ALDH1A1MAPTHSD17B10ITGB3ITGA2B | |
| SCHEMBL7655244 | 0.85 | DRD2 (0.60) | KDM4ESMN1; SMN2ALDH1A1GFERKMT2A | |
| Hydrochloric Acid SCHEMBL8745028 | 0.83 | KDM4E (0.68) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL25370948 | 0.83 | KDM4E (0.80) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL6031705 | 0.83 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL27395515 | 0.83 | KDM4E (0.80) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL8691440 | 0.83 | DRD4 (0.70) | ALDH1A1MAPTITGB3ITGA2BGFER | |
| SCHEMBL11549618 | 0.82 | KDM4E (0.78) | KDM4ESMN1; SMN2ALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL8690310 | 0.82 | DRD4 (0.68) | ITGB3ITGA2BGFERDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |